| Key Benefits and Features of Inertsil C8-3 - Part of the Advanced Inertsil 3-Series of Phases |
 Virtually perfect peak shape for most bases and acids |
 Unique selectivity |
 Exceptional physical and chemical durability provides long column life |
 Vast database of chromatographic applications available to assist in method development |
 Very low operating back pressure |
 Click here for Inertsil C8-3 ordering information | ||||
| Inertsil C8-3 provides pure reverse phase characteristics that are critical to resolving highly polar compounds like acidic and basic pharmaceuticals. The near perfect C8 ( octyl ) phase and end-capping coverage on this material results in symmetric, narrow peaks for even the most polar compounds while using simple eluents like aqueous MeCN or MeOH. The need for ion-pair and competing-amine eluent modifiers that are necessary with many other reverse phase columns is eliminated on Inertsil 3-series phases. The Inertsil 3-series represents a major advance in performance over the original Inertsil 2-Series. Inertsil 3-Series phases, including ODS-3, ODS-3V, ODS-SPRINT , ODS-P, ODS-EP, Ph-3, CN-3, NH2, Diol, and SIL-100Å, are based on a purer, higher surface area silica which is specially manufactured to provide maximum bonded phase coverage. The result is a series of columns which provide excellent peak shapes using simple eluents while operating at low pressure. GL Sciences has compiled a vast collection of chromatographic applications data on C8-3 and their other phases which can assist you in method development. These can be accessed under the "chromatograms" link on the main menu bar above, by searching for a particular compound using our "search" link above, or by clicking here. | Figure 1 - Tanaka Test for Selectivity Column: Inertsil 3 Series 150 x 4.6mm Order No. for Inertsil C8-3: 1032L150W046 Eluent: MeOH:Water 80:20 Flow: 1.0 ml/min Temp: 40°C Detection: UV @ 254nm Sample: 1. caffeine, 2. phenol, 3. n-Butylbenzene, 4. n-amylbenzene, 5. o-terphenyl, 6. triphenylene Notes: The Tanaka test is one of several industry-wide standard tests which illustrate selectivity differences between bonded phases. The wide range of Inertsil Series-3 phases show vast selectivity differences in Tanaka test, allowing a wide array of compounds to be separated.
Inertsil C8-3, along with most of the other Inertsil 3-series phases, are available in 3, 5, and 8 micron particle sizes in column configurations ranging from capillary to 50mm ID preparative sizes. |
| Particle Size(s) | Particle Shape | Surface Area | Pore Size | Pore Volume | Silica Purity | Bonded Phase | End- Capping | Carbon Load | pH Range* |
| 3, 5, 8 µm | Spherical | 450 m2/g | 100Å | 1.05 mL/g | 99.999% | Octyl Groups | Yes | 9% | 2 - 7.5 |
| * Inertsil phases are known to provide excellent results and long column life at pH levels of 9-10. However, optimum column life may be achieved at a pH between 2 and 7.5. | |||||||||
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